Oxidative stress induces club cell proliferation and pulmonary fibrosis in Atp8b1 mutant mice
نویسندگان
چکیده
منابع مشابه
Global gene profiling of aging lungs in Atp8b1 mutant mice
OBJECTIVE Recent studies implicate cardiolipin oxidation in several age-related diseases. Atp8b1 encoding Type 4 P-type ATPases is a cardiolipin transporter. Mutation in Atp8b1 gene or inflammation of the lungs impairs the capacity of Atp8b1 to clear cardiolipin from lung fluid. However, the link between Atp8b1 mutation and age-related gene alteration is unknown. Therefore, we investigated how ...
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ژورنال
عنوان ژورنال: Aging
سال: 2019
ISSN: 1945-4589
DOI: 10.18632/aging.101742